DIVISION OF BASIC SCIENCES - NCI
Unlocking mechanisms of resistance to targeted therapy in thyroid cancer
Unlocking mechanisms of resistance to targeted therapy in thyroid cancer is a funding opportunity from DIVISION OF BASIC SCIENCES - NCI, up to 429350.
Overview
Our major goal is to identify new determinants of resistance to targeted therapy and more specifically to BRAF inhibitors in advanced and metastatic thyroid cancer. Our overall hypothesis is that BRAFV600E driven-ATC cells heavily rely on certain genes or key pathways to survive canonical treatments targeting…