UNIVERSITY OF CONNECTICUT SCH OF MED/DNT
Unique Role of ASPM in Development of Large and Folded Cerebral Cortex
Unique Role of ASPM in Development of Large and Folded Cerebral Cortex is a funding opportunity from UNIVERSITY OF CONNECTICUT SCH OF MED/DNT, up to 636412, closing June 30, 2030.
Jun 30, 2030
(1430d left)Overview
PROJECT SUMMARY/ABSTRACT Neurodevelopmental disorders affecting the large and folded (gyrencephalic) human cerebral cortex require disease mechanisms that are robust in humans but insignificant in mice. For example, loss of ASPM (assembly factor for spindle microtubules) in humans causes severe microcephaly with…