BRIGHAM AND WOMEN'S HOSPITAL
Type 2 Inflammation and Remodeling Elicited Through an LTE4/OXGR1-dependent pathway
Type 2 Inflammation and Remodeling Elicited Through an LTE4/OXGR1-dependent pathway is a funding opportunity from BRIGHAM AND WOMEN'S HOSPITAL, up to 712176, closing December 31, 2028.
Dec 31, 2028
(884d left)Overview
PROJECT SUMMARY Tuft cells are a specialized epithelial cells (EpCs) that initiate airway type 2 inflammation (T2I) through their generation of IL-25 and pro-inflammatory lipid mediators, cysteinyl leukotrienes (CysLTs). We previously reported that airway tuft cells are indirectly activated by common aeroallergens…