SLOAN-KETTERING INST CAN RESEARCH
Tuning KITv CAR T cells for the solid tumor environment
Tuning KITv CAR T cells for the solid tumor environment is a funding opportunity from SLOAN-KETTERING INST CAN RESEARCH, up to 655042, closing July 31, 2029.
Jul 31, 2029
(1097d left)Overview
PROJECT ABSTRACT We developed and translated CD28 costimulated chimeric antigen receptor (M28z CARs) T cells that target mesothelin (MSLN), a cancer-associated antigen that is overexpressed in a majority of solid tumors; 65 patients have been treated in phase I/II trials, with no on-target, off-tumor toxicity. Having…