VETERANS HEALTH ADMINISTRATION
The terminal steps of cortisol and aldosterone biosynthesis
The terminal steps of cortisol and aldosterone biosynthesis is a funding opportunity from VETERANS HEALTH ADMINISTRATION, closing March 31, 2030.
Mar 31, 2030
(1339d left)Overview
Background and Innovation: Excess aldosterone and cortisol production from the human adrenal cortex commonly contributes to hypertension, heart failure, obesity, glucose intolerance, and low bone mass, which are prevalent chronic diseases in Veterans. Cytochromes P450 11B1 and P450 11B2 catalyze the final steps in the…