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MASSACHUSETTS GENERAL HOSPITAL

The role of the osteocyte in responses to osteoporosis anabolic treatment in humans and mice

The role of the osteocyte in responses to osteoporosis anabolic treatment in humans and mice is a funding opportunity from MASSACHUSETTS GENERAL HOSPITAL, up to 340976, closing December 31, 2027.

Funder
MASSACHUSETTS GENERAL HOSPITAL
Funding
340976
Deadline
Dec 31, 2027
(518d left)

Overview

Osteoporosis and other diseases of bone fragility are treated with two classes of drugs: Anti-resorptives (bisphosphonates, antibodies to RANKL) or anabolics, and their sequential or combined use. Anabolics include PTH analogs (Teriparatide and Abaloparatide) and sclerostin antibody (Scl-Ab, Romosozumab) and increase…

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