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UNIVERSITY OF MASSACHUSETTS AMHERST

The role of extracellular matrix quality in the prediction of metastasis-induced skeletal fragility and response to immunotherapy

The role of extracellular matrix quality in the prediction of metastasis-induced skeletal fragility and response to immunotherapy is a funding opportunity from UNIVERSITY OF MASSACHUSETTS AMHERST, up to 392617, closing August 31, 2026.

Funder
UNIVERSITY OF MASSACHUSETTS AMHERST
Funding
392617
Deadline
Aug 31, 2026
(31d left)

Overview

Metastatic bone disease (MBD) is a frequent and fatal complication in patients with advanced solid malignancies. Immune checkpoint inhibitors (ICIs) such as programmed cell death protein-1 (PD-1) have revolutionized cancer therapy over the past decade; however, the positive impact of ICIs in MBD is attenuated due to…

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