MAYO CLINIC ROCHESTER
Sphingolipid Metabolism Controls Regulatory T cell Function and Intestinal Homeostasis
Sphingolipid Metabolism Controls Regulatory T cell Function and Intestinal Homeostasis is a funding opportunity from MAYO CLINIC ROCHESTER, up to 242100, closing August 31, 2027.
Aug 31, 2027
(396d left)Overview
PROJECT ABSTRACT Inflammatory bowel disease (IBD) is characterized by inconsistent response to current therapies and persistent activation of pathogenic effector CD4+ T cells, implying that regulatory T cells (Tregs) are potentially dysfunctional. Recent evidence suggests that inflammatory-like Tregs are present in…