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UNIVERSITY OF CALIFORNIA BERKELEY

Specificity requirements and functional properties of microbiota-reactive peri-weaning Tregs

Specificity requirements and functional properties of microbiota-reactive peri-weaning Tregs is a funding opportunity from UNIVERSITY OF CALIFORNIA BERKELEY, up to 787945, closing May 31, 2031.

Funder
UNIVERSITY OF CALIFORNIA BERKELEY
Funding
787945
Deadline
May 31, 2031
(1765d left)

Overview

PROJECT SUMMARY This application seeks to define the specificity requirements and functional properties of regulatory T cells (Tregs) that maintain tolerance to the microbiota. RORgt+ Tregs generated during an early-life peri-weaning window (from approximately P14 to P28 in mice) are particularly critical for…

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