UNIVERSITY OF CALIFORNIA, SAN DIEGO
Software and algorithms for elucidating the structure, function, and evolution of extrachromosomal DNA
Software and algorithms for elucidating the structure, function, and evolution of extrachromosomal DNA is a funding opportunity from UNIVERSITY OF CALIFORNIA, SAN DIEGO, up to 730904, closing August 31, 2027.
Aug 31, 2027
(396d left)Overview
Project Summary Somatic copy number amplification (SCNA) of tumor promoting oncogenes, and focal copy number amplifi- cations specifically, are a major driver of cancer pathogenicity. Recent results have revealed that that focal oncogene amplification is mediated to a large extent by extrachromosomal DNA (ecDNA) i.e.,…