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RESEARCH INST OF FOX CHASE CAN CTR

Small-molecule exploitation of ZBP1-driven nuclear necroptosis for cancer immunotherapy

Small-molecule exploitation of ZBP1-driven nuclear necroptosis for cancer immunotherapy is a funding opportunity from RESEARCH INST OF FOX CHASE CAN CTR, up to 758985, closing December 31, 2027.

Funder
RESEARCH INST OF FOX CHASE CAN CTR
Funding
758985
Deadline
Dec 31, 2027
(518d left)

Overview

PROJECT SUMMARY/ABSTRACT. Immune checkpoint blockade (ICB) and other immunotherapies have revolutionized cancer treatment, but the non-responsiveness of most cancers to ICB-based monotherapy remains a significant problem. A major reason for the non-responsiveness of these so-called ‘cold’ tumors is that they lack…

Small-molecule exploitation of ZBP1-driven nuclear necroptosis for cancer immunotherapy | Go Fund It Now