UNIVERSITY OF PENNSYLVANIA
Single-component optogenetic tools to bidirectionally control RhoA in mechanotransduction
Single-component optogenetic tools to bidirectionally control RhoA in mechanotransduction is a funding opportunity from UNIVERSITY OF PENNSYLVANIA, up to 91704, closing August 31, 2026.
Aug 31, 2026
(31d left)Overview
ABSTRACT RhoA, a member of the Rho-family of small GTPases, centrally regulates actin organization and actomyosin contractility. RhoA dynamics coordinate actin stress fiber formation, which ultimately determines how cells generate cytoskeletal tension to transmit mechanical forces to/from neighboring cell-cell…