UNIVERSITY OF MICHIGAN AT ANN ARBOR
Secretory Pathway Protein Degradation Maintains Insulin Biogenesis + Secretion
Secretory Pathway Protein Degradation Maintains Insulin Biogenesis + Secretion is a funding opportunity from UNIVERSITY OF MICHIGAN AT ANN ARBOR, up to 785969, closing December 31, 2030.
Dec 31, 2030
(1614d left)Overview
ABSTRACT Pancreatic insulin mass (a combination of ß-cell mass and function in the production and storage of insulin) is linked to blood glucose regulation. Normal islet ß-cells contain more than a billion insulin molecules per cell. To maintain this amount involves the synthesis of ≥ 6,000 new molecules per…