UNIVERSITY OF CHICAGO
Roles for Ets1 in thymic selection and CD8αα IEL development
Roles for Ets1 in thymic selection and CD8αα IEL development is a funding opportunity from UNIVERSITY OF CHICAGO, up to 49538, closing September 29, 2027.
Sep 29, 2027
(425d left)Overview
PROJECT SUMMARY Thymic selection is crucial for generating functional and self-tolerant T cells, yet the mechanisms underlying the development of unconventional T cell lineages, such as CD8αα intraepithelial lymphocytes (IELs), remain poorly understood. CD8αα IELs possess innate-like features and play essential…