SAINT LOUIS UNIVERSITY
Role of oligomeric TDP-43 aggregate intermediates in ALS and frontotemporal dementia
Role of oligomeric TDP-43 aggregate intermediates in ALS and frontotemporal dementia is a funding opportunity from SAINT LOUIS UNIVERSITY, up to 378750, closing January 31, 2027.
Jan 31, 2027
(184d left)Overview
The goal of this grant is to elucidate key mechanisms of TDP-43 aggregation by uncovering how this process leads to pathology and neurotoxicity. TDP-43 aggregation is the pathological hallmark of amyotrophic lateral sclerosis (ALS) and half of frontotemporal dementia (FTD) cases. In addition, TDP-43 lesions are a…