SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE
Rewiring T cell exhaustion with immune checkpoint blockade therapy
Rewiring T cell exhaustion with immune checkpoint blockade therapy is a funding opportunity from SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE, up to 674996, closing July 31, 2026.
Jul 31, 2026
(0d left)Overview
PROJECT SUMMARY The goal of this project is to determine whether it is possible to promote the development and/or maintenance of CD8+ T cells that are essential for anti-tumor responses to PD-1 immune checkpoint blockade (ICB) therapy by targeting PSGL-1 (P-selectin glycoprotein-1). Studies of exhausted CD8 T cells…