UNIVERSITY OF CALIFORNIA BERKELEY
Regulation of TLR trafficking for proper self versus non-self discrimination
Regulation of TLR trafficking for proper self versus non-self discrimination is a funding opportunity from UNIVERSITY OF CALIFORNIA BERKELEY, up to 541171, closing December 31, 2028.
Dec 31, 2028
(884d left)Overview
PROJECT SUMMARY Inappropriate recognition of self nucleic acids (NA) by members of the Toll-like receptor (TLR) family can result in autoimmune diseases such as lupus and psoriasis. TLR7 (and TLR8 in humans) and TLR9 can be activated by self RNA and DNA, respectively, so defining the mechanisms that limit responses by…