BRIGHAM AND WOMEN'S HOSPITAL
Prostaglandin E2-Dependent Control of a Mast Cell IL-33/ST2 Pathway in Asthma
Prostaglandin E2-Dependent Control of a Mast Cell IL-33/ST2 Pathway in Asthma is a funding opportunity from BRIGHAM AND WOMEN'S HOSPITAL, up to 859874, closing March 31, 2028.
Mar 31, 2028
(609d left)Overview
Abstract This proposal focuses on the potential role of mast cells in the control of type 2 immunopathology (T2I) elicited by IL-33, a principal effector cytokine involved in the onset and persistence of upper and lower airway inflammation. Preliminary studies demonstrate that mast cells are required to drive type 2…