DANA-FARBER CANCER INST
Project 2
Project 2 is a funding opportunity from DANA-FARBER CANCER INST, up to 423518, closing July 31, 2027.
Jul 31, 2027
(365d left)Overview
Summary/Abstract SMARCA4-mutant NSCLC represents a prevalent, aggressive subset in urgent need of effective therapies. SMARCA4 encodes BRG1, a key ATPase subunit of the SWItch/Sucrose Non-Fermentable (SWI/SNF) chromatin remodeling complex. SMARCA4 mutations are present in 9-11% of patients with NSCLC, with truncating,…