ALBERT EINSTEIN COLLEGE OF MEDICINE
Prevention and Therapy of Inflammation Associated Colorectal Cancer
Prevention and Therapy of Inflammation Associated Colorectal Cancer is a funding opportunity from ALBERT EINSTEIN COLLEGE OF MEDICINE, up to 196350, closing December 31, 2026.
Dec 31, 2026
(153d left)Overview
This application is focused on the synthesis and development of MTDIA, a novel transition state inhibitor of MTAP (5'-methylthioadenosine phosphorylase) in the S-adenosylmethionine (SAM) salvage pathway, and our recently synthesized MTDIA pro-drugs with improved pharmacodynamics. This was based on solving the…