ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
Pilot project to elucidate the role of DDX60L in Ebola virus disease
Pilot project to elucidate the role of DDX60L in Ebola virus disease is a funding opportunity from ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, up to 183875, closing April 30, 2027.
Apr 30, 2027
(273d left)Overview
SUMMARY Preliminary Data, based on siRNA knockdown studies, suggests that host encoded DExD/H box family protein DDX60L exerts anti-Ebola virus (EBOV) activity. We therefore hypothesize that DDX60L is a negative regulator of EBOV replication that can influence EBOV disease (EVD). While constitutively expressed in a…