UNIVERSITY OF PENNSYLVANIA
Novel macrophage-tropic transmitted/founder SHIV model of CNS persistence to evaluate CRISPR/Cas9 gene editing
Novel macrophage-tropic transmitted/founder SHIV model of CNS persistence to evaluate CRISPR/Cas9 gene editing is a funding opportunity from UNIVERSITY OF PENNSYLVANIA, up to 696272, closing April 30, 2027.
Apr 30, 2027
(273d left)Overview
Project Summary/Abstract. An eradicative HIV cure requires safe and effective clearance of replication competent virus from all reservoirs, including the brain. Characterization of the CNS reservoir and empiric testing of novel cure strategies require physiologically relevant animal models of HIV persistence in the…