UNIVERSITY OF CINCINNATI
Neuromodulatory regulation of synaptic plasticity in spinal nociceptive circuits
Neuromodulatory regulation of synaptic plasticity in spinal nociceptive circuits is a funding opportunity from UNIVERSITY OF CINCINNATI, up to 601309, closing May 31, 2029.
May 31, 2029
(1035d left)Overview
Project Summary/Abstract Long-term potentiation (LTP) of primary afferent synapses onto spinal projection neurons (PNs) has been linked to increased pain sensitivity. The timing rules controlling the generation of LTP in adult PNs can be persistently relaxed by neonatal tissue damage, which likely contributes to the…