OAKLAND UNIVERSITY
Molecular and cellular mechanisms of spinocerebellar ataxia type 5
Molecular and cellular mechanisms of spinocerebellar ataxia type 5 is a funding opportunity from OAKLAND UNIVERSITY, up to 505394, closing June 30, 2028.
Jun 30, 2028
(700d left)Overview
β-III-spectrin is a key cytoskeletal protein that localizes to the soma and dendrites of cerebellar Purkinje neurons, and is required for dendritic arborization and signaling. Dominant mutations in the SPTBN2 gene encoding β-III-spectrin cause the neurodegenerative disorder spinocerebellar ataxia type 5 (SCA5). SCA5…