UNIVERSITY OF CALIFORNIA SANTA CRUZ
Mechanisms of Translational Surveillance
Mechanisms of Translational Surveillance is a funding opportunity from UNIVERSITY OF CALIFORNIA SANTA CRUZ, up to 318858, closing June 30, 2027.
Jun 30, 2027
(334d left)Overview
Project Summary/Abstract A substantial fraction of human inherited disease-causing mutations introduce an early stop codon that truncates protein production and elicits mRNA decay in a process called Nonsense-Mediated mRNA Decay (NMD). Despite much work, it is still unclear how early stop codons are recognized and how…