JOHNS HOPKINS UNIVERSITY
Imaging the alpha7 nicotinic acetylcholine receptor in mild cognitive impairment
Imaging the alpha7 nicotinic acetylcholine receptor in mild cognitive impairment is a funding opportunity from JOHNS HOPKINS UNIVERSITY, up to 753105, closing January 31, 2027.
Jan 31, 2027
(184d left)Overview
PROJECT SUMMARY This project will assess the availability of the cerebral α7 nicotinic acetylcholine receptor (α7-nAChR) as a contributing factor in the early pathophysiology of Alzheimer's disease (AD). Converging data suggest that the α7-nAChR promotes accumulation of Aβ42 in cholinergic neurons, particularly in…