UNIVERSITY OF PENNSYLVANIA
Identifying regulatory uORFs as a targetable axis for hereditary disease
Identifying regulatory uORFs as a targetable axis for hereditary disease is a funding opportunity from UNIVERSITY OF PENNSYLVANIA, up to 404023, closing May 31, 2027.
May 31, 2027
(304d left)Overview
Abstract The aim of this grant is to identify and validate for therapeutic intervention, regulatory elements within the 5’ untranslated regions (UTR) of protein coding genes, known as upstream open reading frames (uORFs). In so doing, we aim to modulate the protein output from selected genes, offering a novel,…