UNIVERSITY OF CALIFORNIA LOS ANGELES
High throughput multidimensional chemoproteomics for function-directed covalent target discovery
High throughput multidimensional chemoproteomics for function-directed covalent target discovery is a funding opportunity from UNIVERSITY OF CALIFORNIA LOS ANGELES, up to 649181, closing July 31, 2028.
Jul 31, 2028
(731d left)Overview
PROJECT SUMMARY/ABSTRACT Cysteine-reactive drugs are an exciting class of therapeutics that offer the benefits of high potency, occupancy and increased selectivity. Motivated by the clinical success of recent cancer therapeutics that engage specific cysteines, including neratinib and ibrutinib, the discovery of…