FRED HUTCHINSON CANCER CENTER
Genetic and molecular basis for SRSF2 mutations in myelodysplasia
Genetic and molecular basis for SRSF2 mutations in myelodysplasia is a funding opportunity from FRED HUTCHINSON CANCER CENTER, up to 764771, closing April 30, 2029.
Apr 30, 2029
(1004d left)Overview
Mutations in genes encoding RNA splicing factors are the single most common class of genetic alterations in patients with myelodysplastic syndromes (MDS). Recurrent mutations affecting SF3B1, SRSF2, and U2AF1 are the most common and occur as heterozygous point mutations at specific amino acid residues. In the first…