UNIVERSITY OF WISCONSIN-MADISON
Dynamic reprogramming of macrophage acetyl-CoA metabolism in endotoxin tolerance
Dynamic reprogramming of macrophage acetyl-CoA metabolism in endotoxin tolerance is a funding opportunity from UNIVERSITY OF WISCONSIN-MADISON, up to 40585, closing September 3, 2027.
Sep 3, 2027
(399d left)Overview
PROJECT SUMMARY / ABSTRACT Macrophages play a pivotal role in maintaining homeostasis by tightly regulating the inflammatory response. In response to endotoxins like lipopolysaccharide, they undergo dynamic reprogramming, transitioning from a pro-inflammatory to suppressive to tolerant state, resulting in endotoxin…