BETH ISRAEL DEACONESS MEDICAL CENTER
Detection of PD-1 inhibitory signaling and its molecular relays in T cells: Implications for cancer immunotherapy
Detection of PD-1 inhibitory signaling and its molecular relays in T cells: Implications for cancer immunotherapy is a funding opportunity from BETH ISRAEL DEACONESS MEDICAL CENTER, up to 711511, closing December 31, 2027.
Dec 31, 2027
(518d left)Overview
PD-1 blocking agents have achieved significant success as anti-cancer therapeutics. The mechanism(s) of how PD-1 compromises anti-tumor function remain poorly understood. Although in trans engagement of PD-1 expressed in T cells by its ligands expressed on APC or cancer cells inhibits T cell activation, evolving…