DIVISION OF BASIC SCIENCES - NCI
Design of novel antitumor immunotherapies based on tumor-associated glycopeptide antigens
Design of novel antitumor immunotherapies based on tumor-associated glycopeptide antigens is a funding opportunity from DIVISION OF BASIC SCIENCES - NCI, up to 472388.
Overview
Specific Aim 1. Optimization of both active (vaccine) and passive (antibodies) MUC4-TF-based agents for combined tumor immunotherapy: The commercialized antibody discussed in the last cycle was a first successful attempt at discovering a tumor-selective glycopeptide-based mAb. We have completed a biodistribution study…