Decoding Nuclear Mechanosignaling and Epigenetic Mediators of Mechanical Memory in Cardiomyocytes

Overview

Project summary Mechanotransduction is the process by which cells convert external mechanical signals into biochemical signals that shape their phenotypic adaptations. In cardiomyocytes, short-term extracellular stiffening induces readily reversible phenotypic adaptations, while sustained exposure to extracellular…