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UNIV OF MARYLAND, COLLEGE PARK

Characterizing NLRP11 Activation by Mycobacteria to Enhance Innate Immune Responses

Characterizing NLRP11 Activation by Mycobacteria to Enhance Innate Immune Responses is a funding opportunity from UNIV OF MARYLAND, COLLEGE PARK, up to 421720, closing January 31, 2028.

Funder
UNIV OF MARYLAND, COLLEGE PARK
Funding
421720
Deadline
Jan 31, 2028
(549d left)

Overview

The NLRP11 protein is only expressed in primates and participates in the activation of the canonical NLRP3 and non-canonical caspase-4 inflammasome activation after infection with gram-negative bacteria. We found that the atypical gram-positive pathogen Mycobacterium tuberculosis (Mtb) and the opportunistic pathogen…

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