HARVARD MEDICAL SCHOOL
Cell-type-specific dysregulation and genetic control of alternative polyadenylation in neurodegeneration
Cell-type-specific dysregulation and genetic control of alternative polyadenylation in neurodegeneration is a funding opportunity from HARVARD MEDICAL SCHOOL, up to 125901, closing May 31, 2027.
May 31, 2027
(304d left)Overview
PROJECT SUMMARY/ABSTRACT Alternative polyadenylation (APA) is the fundamental mechanism for 3’ UTR choice during mRNA maturation, directly affecting mRNA localization, translation, and stability. Proper control of 3’UTR choice is crucial in the brain, especially for precise localization of stable mRNAs in highly…