WEST VIRGINIA UNIVERSITY
CD38-Driven Metabolic and Immune Remodeling in Glioblastoma
CD38-Driven Metabolic and Immune Remodeling in Glioblastoma is a funding opportunity from WEST VIRGINIA UNIVERSITY, up to 239753, closing June 30, 2028.
Jun 30, 2028
(700d left)Overview
Glioblastoma (GBM) is the most aggressive brain malignancy, characterized by profound metabolic reprogramming and an immunosuppressive tumor microenvironment (TME). CD38 is a multifunctional ectoenzyme that hydrolyzes NAO+, generating adenosine and cyclic ADP-ribose while depleting extracellular NAO+, thereby…