SLOAN-KETTERING INST CAN RESEARCH
CD28-KITv CAR T cells with PD-1 dominant negative receptor
CD28-KITv CAR T cells with PD-1 dominant negative receptor is a funding opportunity from SLOAN-KETTERING INST CAN RESEARCH, up to 2639991, closing February 28, 2029.
Feb 28, 2029
(944d left)Overview
PROJECT ABSTRACT The success of chimeric antigen receptor (CAR) T-cell therapy in solid tumors requires antigen targets with no on-target, off-tumor toxicity, effective tumor infiltration, cytotoxicity and proliferation in an immunosuppressive environment, and revival of antigen stress-induced exhausted CAR T cells.…