UNIVERSITY OF MICHIGAN AT ANN ARBOR
B12 Trafficking and Inherited Defects
B12 Trafficking and Inherited Defects is a funding opportunity from UNIVERSITY OF MICHIGAN AT ANN ARBOR, up to 539014, closing January 31, 2028.
Jan 31, 2028
(549d left)Overview
Vitamin B12 (or cobalamin) supports just two enzymes in the human proteome, but its absence is incompatible with life. This high value dietary commodity is escorted by an elaborate system of chaperones to its two client enzymes: methionine synthase (MS) in the cytoplasm and methylmalonyl-CoA mutase (MCM) in the…