BRIGHAM AND WOMEN'S HOSPITAL
Arid5b regulation of pathogenic fibroblast states
Arid5b regulation of pathogenic fibroblast states is a funding opportunity from BRIGHAM AND WOMEN'S HOSPITAL, up to 367355, closing April 30, 2031.
Apr 30, 2031
(1734d left)Overview
In RA, the synovial membrane becomes profoundly infiltrated with T cells, B cells, macrophages and other inflammatory leukocytes. As a mesenchymal tissue, it also undergoes striking hyperplasia of the parenchymal synovial fibroblasts. Appreciation for the central role that the synovial fibroblasts play in the disease…