UNIVERSITY OF CALIFORNIA-IRVINE
Amplified femtosecond laser permeabilization and poration for nonviral corneal gene delivery
Amplified femtosecond laser permeabilization and poration for nonviral corneal gene delivery is a funding opportunity from UNIVERSITY OF CALIFORNIA-IRVINE, up to 431750, closing April 30, 2027.
Apr 30, 2027
(273d left)Overview
Abstract In the cornea, topical application is the most desired method for administration of gene therapy, but the effective delivery to the corneal stroma is limited by two major factors. First, tight junctions between epithelial cells create a highly effective barrier to large molecule diffusion. Second, the…