NATIONAL INSTITUTE ON AGING
ALZHEIMERS RESEARCH PROJECT: CARD - Senescent Phenotypes of Isogenic iPSC-Derived Alzheimer's Disease and Related Dementia Models at Cellular Resolution
ALZHEIMERS RESEARCH PROJECT: CARD - Senescent Phenotypes of Isogenic iPSC-Derived Alzheimer's Disease and Related Dementia Models at Cellular Resolution is a funding opportunity from NATIONAL INSTITUTE ON AGING, up to 26495.
Overview
Toward our aim of developing a neuronal model to quantify and induce cellular senescence, we have explored senescence induction with two types of stimuli ad different doses: doxorubicin treatment and SLO treatment. We assessed senescence signatures using multiple methods: transcriptomic, proteomics, activity assays,…