NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES
Advancing Cryo-EM to Study Conformational Dynamics of Macromolecular Complexes from In Vitro to In Situ
Advancing Cryo-EM to Study Conformational Dynamics of Macromolecular Complexes from In Vitro to In Situ is a funding opportunity from NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES, up to 1291900.
Overview
In FY2025, this project advanced structural studies of macromolecular complexes across a continuum that spans purified assemblies to their native cellular environments. Using cryogenic electron microscopy (cryo-EM) and cryo-electron tomography (cryo-ET), we refined workflows that capture conformational dynamics…