UNIVERSITY OF MICHIGAN AT ANN ARBOR
Activation of androgen biosynthesis and drug metabolism by cytochrome b5
Activation of androgen biosynthesis and drug metabolism by cytochrome b5 is a funding opportunity from UNIVERSITY OF MICHIGAN AT ANN ARBOR, up to 405600, closing July 31, 2029.
Jul 31, 2029
(1096d left)Overview
Abstract Cytochrome b5 (b5) profoundly influences the catalytic efficiency of many cytochrome P450-catalyzed reactions, yet the mechanism(s) of this action of b5 on P450 enzymes are controversial. Among these b5- regulated activities is the 17,20-lyase activity of P450 17A1 (steroid 17-hydroxylase/17,20-lyase), which…