GEORGETOWN UNIVERSITY
A novel murine model of 2-Hydroxyglutaric aciduria
A novel murine model of 2-Hydroxyglutaric aciduria is a funding opportunity from GEORGETOWN UNIVERSITY, up to 156000, closing August 31, 2026.
Aug 31, 2026
(31d left)Overview
Compound heterozygous missense mutations of the SLC25A1 gene give raise to combined D/L-2- HydroxyGlutaric Aciduria (D/L-2HGA) [1-10], a disease hallmarked by the accumulation of the two enantiomeric forms of 2-hydroxyglutaric acid (2HG), D and L. D/L-2HGA is considered a rare disorder, with 150 cases described…